Fred R Hirsch Selected Research

Proteins (Proteins, Gene)

9/2023	Role of Lactate in the Regulation of Transcriptional Activity of Breast Cancer-Related Genes and Epithelial-to-Mesenchymal Transition Proteins: A Compassion of MCF7 and MDA-MB-231 Cancer Cell Lines.
3/2023	Protein Expression of immune checkpoints STING and MHCII in small cell lung cancer.
5/2022	Loss of STING expression is prognostic in non-small cell lung cancer.
1/2022	EGFR High Copy Number Together With High EGFR Protein Expression Predicts Improved Outcome for Cetuximab-based Therapy in Squamous Cell Lung Cancer: Analysis From SWOG S0819, a Phase III Trial of Chemotherapy With or Without Cetuximab in Advanced NSCLC.
1/2022	Expression patterns and prognostic relevance of subtype-specific transcription factors in surgically resected small-cell lung cancer: an international multicenter study.
10/2020	Round Robin Evaluation of MET Protein Expression in Lung Adenocarcinomas Improves Interobserver Concordance.
1/2020	EURACAN/IASLC Proposals for Updating the Histologic Classification of Pleural Mesothelioma: Towards a More Multidisciplinary Approach.
1/2020	Comprehensive Immune Profiling of Medullary Thyroid Cancer.
12/2019	T cell immunoglobulin and mucin-domain containing-3 in non-small cell lung cancer.
10/2019	Galectin-9 in non-small cell lung cancer.

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Fred R Hirsch Research Topics

Disease

140	Neoplasms (Cancer) 12/2023 - 05/2002
131	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2024 - 02/2002
122	Lung Neoplasms (Lung Cancer) 03/2024 - 02/2002
20	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 11/2023 - 05/2002
19	Adenocarcinoma 05/2022 - 02/2002
14	Neoplasm Metastasis (Metastasis) 11/2023 - 05/2002
13	Adenocarcinoma of Lung 01/2021 - 02/2011
12	Disease Progression 09/2021 - 09/2011
8	Carcinogenesis 09/2023 - 03/2002
8	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021 - 02/2002
8	Carcinoma (Carcinomatosis) 01/2021 - 07/2002
8	Squamous Cell Carcinoma of Head and Neck 01/2017 - 09/2006
7	Mesothelioma 11/2023 - 01/2017
5	Breast Neoplasms (Breast Cancer) 09/2023 - 02/2002
5	Bronchiolo-Alveolar Adenocarcinoma (Adenocarcinoma, Bronchiolo Alveolar) 01/2018 - 10/2003
5	Colorectal Neoplasms (Colorectal Cancer) 04/2013 - 03/2009
4	Malignant Mesothelioma 01/2020 - 09/2012
4	Exanthema (Rash) 01/2018 - 03/2015
4	Hemorrhage 01/2017 - 04/2009
3	COVID-19 08/2022 - 01/2022
3	Anemia 04/2021 - 08/2003
3	Lymphatic Metastasis 12/2019 - 01/2013
3	Chronic Obstructive Pulmonary Disease (COPD) 11/2007 - 01/2004
2	Infections 11/2023 - 08/2022
2	Bites and Stings (Sting) 03/2023 - 05/2022
2	Pneumonia (Pneumonitis) 01/2022 - 01/2017
2	Acne Vulgaris 01/2018 - 07/2015
2	Lymphoma (Lymphomas) 01/2018 - 01/2017
2	Ovarian Neoplasms (Ovarian Cancer) 06/2016 - 12/2015

Drug/Important Bio-Agent (IBA)

68	ErbB Receptors (EGF Receptor)IBA 11/2023 - 02/2002
58	Biomarkers (Surrogate Marker)IBA 03/2024 - 07/2002
44	Proteins (Proteins, Gene)FDA Link 09/2023 - 02/2002
41	Tyrosine Kinase InhibitorsIBA 11/2023 - 08/2005
22	Gefitinib (Iressa)FDA Link 10/2018 - 05/2005
17	B7-H1 AntigenIBA 01/2023 - 07/2015
17	Cetuximab (Erbitux)FDA Link 01/2022 - 04/2008
17	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2018 - 12/2006
15	Immune Checkpoint InhibitorsIBA 03/2024 - 01/2018
15	Monoclonal AntibodiesIBA 11/2023 - 02/2002
12	PlatinumIBA 11/2023 - 09/2006
11	Messenger RNA (mRNA)IBA 11/2020 - 05/2006
9	RNA (Ribonucleic Acid)IBA 12/2023 - 07/2002
9	AntibodiesIBA 11/2023 - 03/2008
9	Pemetrexed (MTA)FDA Link 01/2016 - 02/2011
8	LigandsIBA 01/2021 - 05/2005
8	CrizotinibIBA 04/2016 - 09/2012
7	Anaplastic Lymphoma KinaseIBA 01/2019 - 01/2011
7	Paclitaxel (Taxol)FDA LinkGeneric 03/2016 - 08/2008
6	MucinsIBA 02/2021 - 02/2011
6	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 10/2020 - 12/2006
6	Carboplatin (JM8)FDA LinkGeneric 03/2016 - 08/2008
6	DNA (Deoxyribonucleic Acid)IBA 08/2011 - 12/2002
5	MicroRNAs (MicroRNA)IBA 08/2018 - 02/2013
5	Bevacizumab (Avastin)FDA Link 01/2018 - 02/2011
5	Cisplatin (Platino)FDA LinkGeneric 01/2017 - 03/2015
5	Trastuzumab (Herceptin)FDA Link 02/2004 - 02/2002
4	Cadherins (E-Cadherin)IBA 09/2023 - 05/2002
4	Immunoglobulins (Immunoglobulin)IBA 02/2021 - 01/2018
4	Phosphotransferases (Kinase)IBA 01/2020 - 01/2017
4	SilverIBA 01/2019 - 02/2012
4	Cell-Free Nucleic AcidsIBA 03/2018 - 01/2017
4	necitumumabIBA 01/2018 - 03/2015
4	Gemcitabine FDA Link 01/2016 - 05/2002
4	CarcinogensIBA 09/2009 - 03/2002
3	atezolizumabIBA 12/2023 - 10/2018
3	AfatinibIBA 01/2022 - 01/2014
3	NivolumabIBA 09/2021 - 01/2018
3	IpilimumabIBA 09/2021 - 01/2018
3	ponatinibIBA 01/2019 - 06/2014
3	ORALIT (ORS)IBA 01/2017 - 06/2004
3	Vinorelbine (Navelbine)FDA LinkGeneric 01/2017 - 09/2008
3	GoldIBA 08/2013 - 11/2009
3	Volatile Organic CompoundsIBA 08/2013 - 11/2009
3	Insulin (Novolin)FDA Link 07/2013 - 05/2010
3	Thymidylate SynthaseIBA 01/2013 - 04/2012
3	Insulin-Like PeptidesIBA 12/2010 - 08/2008
3	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 10/2010 - 05/2005
3	Indicators and Reagents (Reagents)IBA 04/2010 - 08/2005
3	SmokeIBA 09/2009 - 03/2002
2	CytokinesIBA 12/2023 - 01/2023
2	durvalumabIBA 06/2023 - 01/2021
2	Transcription Factors (Transcription Factor)IBA 01/2022 - 06/2013
2	VaccinesIBA 01/2022 - 01/2009
2	Docetaxel (Taxotere)FDA Link 01/2022 - 11/2013
2	Hemoglobins (Hemoglobin)IBA 04/2021 - 09/2006
2	Formaldehyde (Formol)FDA Link 10/2020 - 02/2013
2	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2019 - 01/2018
2	Angiogenesis InhibitorsIBA 01/2019 - 01/2018
2	onartuzumabIBA 01/2017 - 09/2014

Therapy/Procedure

90	Therapeutics 03/2024 - 05/2002
37	Drug Therapy (Chemotherapy) 11/2023 - 08/2003
30	Immunotherapy 06/2023 - 01/2016
12	Chemoprevention 02/2013 - 02/2002
8	Radiotherapy 06/2023 - 08/2003
5	Precision Medicine 01/2018 - 10/2010
2	Chemoradiotherapy 06/2023 - 01/2013
2	Neoadjuvant Therapy 01/2020 - 12/2018
2	Pneumonectomy (Lung Volume Reduction) 01/2020 - 12/2002
2	Aftercare (After-Treatment) 01/2017 - 06/2007
2	Molecular Targeted Therapy 01/2017 - 08/2003